Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077730 | 0.82 | HTT (0.53) | TAAR1AOC3MAOBIDO1MEN1 | |
| SCHEMBL8071578 | 0.82 | MMP12 (0.42) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL810464 | 0.78 | ALDH1A1 (0.38) | — | |
| SCHEMBL22850008 | 0.74 | MMP12 (0.44) | TAAR1AOC3KCNH2TMEM97SLC6A2 | |
| SCHEMBL436099 | 0.74 | AOC3 (0.52) | TAAR1AOC3KCNH2TMEM97SLC6A2 | |
| Hydrochloric Acid SCHEMBL27666375 | 0.72 | AOC3 (0.50) | TAAR1AOC3KCNH2TMEM97SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL10725614 | 0.72 | AOC3 (0.50) | TAAR1AOC3KCNH2TMEM97SLC6A2 | |
| SCHEMBL28210143 | 0.72 | TAAR1 (0.48) | TAAR1AOC3KCNH2TMEM97SLC6A2 | |
| Hydrochloric Acid SCHEMBL4443325 | 0.72 | IDO1 (0.51) | AOC3PPARGPPARAIDO1MEN1 | |
| SCHEMBL21175025 | 0.71 | TAAR1 (0.47) | TAAR1AOC3KCNH2TMEM97SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411942-A4 | SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS | SYNAPTIC PHARMA CORP (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1411942-A1 | SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS | Synaptic Pharmaceutical Corporation (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003004027-A1 | SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2003-01-16 | — | — | WO | disclosed |