Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090318 | 0.98 | CNR2 (0.39) | CNR2L3MBTL1ALOX5APALDH1A1PIM1 | |
| SCHEMBL6225570 | 0.95 | CNR2 (0.37) | CNR2L3MBTL1ALOX5APALDH1A1PIM1 | |
| SCHEMBL29508914 | 0.71 | ALOX5AP (0.49) | CNR2L3MBTL1ALOX5APALDH1A1PIM1 | |
| SCHEMBL22858424 | 0.71 | ALOX5AP (0.49) | CNR2L3MBTL1ALOX5APALDH1A1PIM1 | |
| SCHEMBL16097729 | 0.70 | CNR2 (0.42) | CNR2L3MBTL1ALOX5APALDH1A1PIM1 | |
| SCHEMBL9189981 | 0.70 | HSD17B10 (0.46) | L3MBTL1ALOX5APALDH1A1PIM1HSD17B10 | |
| SCHEMBL11112437 | 0.70 | ALOX5AP (0.46) | L3MBTL1ALOX5APPIM1HSD17B10MEN1 | |
| SCHEMBL24759988 | 0.69 | CNR2 (0.41) | CNR2L3MBTL1ALOX5APALDH1A1PIM1 | |
| SCHEMBL25205450 | 0.69 | ALOX5AP (0.40) | CNR2L3MBTL1ALOX5APALDH1A1PIM1 | |
| SCHEMBL31093334 | 0.68 | ALDH1A1 (0.46) | CNR2L3MBTL1ALDH1A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572215-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | GLAXO GROUP LIMITED (GB) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056369-A1 | BENZO ‘ D!AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |