Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924962 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14469578 | 0.82 | SMN1; SMN2 (0.82) | SMN1; SMN2KMT2AMEN1ALDH1A1CASR | |
| SCHEMBL2238765 | 0.81 | NCF1 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL79765 | 0.79 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AMEN1ALDH1A1CASR | |
| SCHEMBL29560 | 0.79 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AMEN1ALDH1A1CASR | |
| SCHEMBL774613 | 0.79 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AMEN1ALDH1A1CASR | |
| Hydrochloric Acid SCHEMBL5493749 | 0.77 | SMN1; SMN2 (0.79) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27939948 | 0.77 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AMEN1ALDH1A1CASR | |
| Hydrochloric Acid SCHEMBL9635019 | 0.77 | SMN1; SMN2 (0.79) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27830673 | 0.77 | SMN1; SMN2 (0.79) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509497-A1 | CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES | Amgen Inc. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099776-A1 | CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES | AMGEN INC. (US) | 2003-12-04 | — | — | WO | disclosed |