Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6225952

CC(C)CCN.O=C(O)C(F)(F)F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.48
ODC1 P11926 2/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HRH4 Q9H3N8 2/20 0.38
HRH3 Q9Y5N1 2/20 0.38
GABBR2 O75899 2/20 0.37
GABBR1 Q9UBS5 2/20 0.37
DPP8 Q6V1X1 2/20 0.36
DPP7 Q9UHL4 2/20 0.36
DPP4 P27487 1/20 0.36
GSR P00390 1/20 0.35
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2475408 0.83 CACNA2D1 (0.41) GABRR1ODC1DPP8DPP7DPP4
Trifluoroacetic Acid SCHEMBL8529046 0.83 GABRR1 (0.45) GABRR1ODC1KDM4ELMNAMAPT
Trifluoroacetic Acid SCHEMBL21199352 0.82 GABRR1 (0.41) GABRR1ODC1HRH4HRH3GABBR2
Trifluoroacetic Acid SCHEMBL29019099 0.81 GABRR1 (0.41) GABRR1ODC1KDM4ELMNAMAPT
Trifluoroacetic Acid SCHEMBL30164390 0.78 BLM (0.43) BLMPMP22DPP8DPP7DPP4
Trifluoroacetic Acid SCHEMBL27664147 0.78 BLM (0.43) BLMPMP22DPP8DPP7DPP4
Trifluoroacetic Acid SCHEMBL30140901 0.78 BLM (0.43) BLMPMP22DPP8DPP7DPP4
Trifluoroacetic Acid SCHEMBL3149196 0.78 ODC1 (0.48) GABRR1ODC1KDM4ELMNAMAPT
Trifluoroacetic Acid SCHEMBL10619767 0.78 ODC1 (0.48) GABRR1ODC1KDM4ELMNAMAPT
Trifluoroacetic Acid SCHEMBL6490887 0.78 HRH4 (0.50) GABRR1ODC1KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867654-A RNA constructs and uses thereof 生物技术欧洲股份公司 2023-03-28 CN disclosed
CN-115843330-A Coronavirus vaccine 辉瑞公司 2023-03-24 CN disclosed
CN-115811986-A Coronavirus vaccine 生物技术欧洲股份公司 2023-03-17 CN disclosed
CN-115569151-A Adipose tissue-derived stromal stem cells for the treatment of refractory, complex perianal fistulas in crohn's disease 武田药品工业株式会社 2023-01-06 CN disclosed
CN-115427432-A Vaccine agent for treating or preventing coronavirus disease mutant strain 斯微(上海)生物科技股份有限公司 2022-12-02 CN disclosed
CN-108883135-B Adipose tissue-derived stromal stem cells for the treatment of refractory, complex perianal fistulas in crohn's disease 武田药品工业株式会社 2022-11-04 CN disclosed
US-11364259-B2 MRNA functionalization method THE UNIVERSITY OF TOKYO (JP) 2022-06-21 US disclosed
WO-2022004765-A1 COMPOSITION FOR GENOME EDITING 公益財団法人川崎市産業振興財団 2022-01-06 WO disclosed
CN-113521269-A Coronavirus vaccine 生物技术RNA制药有限公司 2021-10-22 CN disclosed
CN-113521268-A Coronavirus vaccine 生物技术RNA制药有限公司 2021-10-22 CN disclosed
WO-2021131116-A1 CARRIER FOR CELL DELIVERY 株式会社アイ・ティー・オー 2021-07-01 WO disclosed
US-20200347385-A1 METHOD FOR mRNA STABILIZATION THE UNIVERSITY OF TOKYO (JP) 2020-11-05 US disclosed
EP-3708664-A1 METHOD FOR mRNA STABILIZATION The University Of Tokyo (JP) 2020-09-16 EP disclosed
EP-3564375-A1 MRNA FUNCTIONALIZATION METHOD The University Of Tokyo (JP) 2019-11-06 EP disclosed
US-20190328769-A1 MRNA FUNCTIONALIZATION METHOD THE UNIVERSITY OF TOKYO (JP) 2019-10-31 US disclosed
EP-1514869-A1 INDOLE, INDAZOLE, AND BENZAZOLE DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2005-03-16 EP disclosed
EP-0190891-A2 Novel amino acid derivatives Kissei Pharmaceutical Co. Ltd. (JP) 1986-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11364259-B2 MRNA functionalization method RNGTT, RNMT, NSUN3 GABRR1 1678/4885ODC1 1957/4885KDM4E 4252/4885
US-20190328769-A1 MRNA FUNCTIONALIZATION METHOD RNGTT, RNMT, NSUN3 GABRR1 1678/4885ODC1 1957/4885KDM4E 4252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.