Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 15/20 | 0.60 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030246 | 0.87 | HPGD (0.62) | HPGDGRIA3GRIA4AR | |
| SCHEMBL6227279 | 0.86 | HPGD (0.45) | HPGDPRMT3 | |
| SCHEMBL12466410 | 0.77 | EGFR (0.53) | HPGD | |
| SCHEMBL30533141 | 0.77 | EGFR (0.53) | HPGD | |
| SCHEMBL23637039 | 0.76 | VNN1 (0.52) | POLB | |
| SCHEMBL22622336 | 0.76 | L3MBTL3 (0.70) | HPGD | |
| SCHEMBL20467429 | 0.76 | HPGD (1.00) | HPGD | |
| SCHEMBL28850937 | 0.75 | EGFR (0.51) | PRMT3 | |
| SCHEMBL2051696 | 0.75 | EGFR (0.56) | AR | |
| SCHEMBL1105475 | 0.75 | EGFR (0.51) | HPGDPRMT3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583757-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-10-12 | — | — | EP | claimed |
| WO-2004058743-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | claimed |