Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.57 |
| ▸ | GABRD | O14764 | 2/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.57 |
| ▸ | GABRE | P78334 | 2/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391455 | 0.84 | CA1 (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL38661880 | 0.81 | HDAC1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5103850 | 0.81 | MEN1 (0.54) | KDM4EMAPTSMN1; SMN2HDAC1MEN1 | |
| SCHEMBL3953891 | 0.80 | HDAC1 (0.55) | KDM4ESMN1; SMN2HDAC1MEN1KMT2A | |
| SCHEMBL9651918 | 0.79 | HDAC1 (0.70) | KDM4EMAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL29904755 | 0.79 | HDAC1 (0.70) | KDM4EMAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL27736941 | 0.79 | KDM4E (0.59) | L3MBTL1KDM4EHDAC1POLBNPC1 | |
| SCHEMBL28304223 | 0.77 | AAK1 (0.47) | L3MBTL1KDM4ECA1CA2HDAC1 | |
| SCHEMBL15416460 | 0.75 | LMNA (0.57) | MAPTSMN1; SMN2HDAC1MEN1KMT2A | |
| SCHEMBL7324248 | 0.74 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583757-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004058743-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | disclosed |