SCHEMBL622694

SCHEMBL622694

O=C(O)C(c1ccccc1)N1CC[C@@H](F)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
GAA P10253 1/20 0.57
KDM4E B2RXH2 2/20 0.48
HRH1 P35367 7/20 0.44
CCR3 P51677 7/20 0.44
KCNH2 Q12809 4/20 0.44
TSHR P16473 3/20 0.43
ALDH1A1 P00352 5/20 0.43
DPP4 P27487 1/20 0.43
DPP7 Q9UHL4 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
ALOX15 P16050 1/20 0.40
XIAP P98170 1/20 0.40
HKDC1 Q2TB90 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12137589 1.00 LMNA (0.58) LMNAGAAKDM4EHRH1CCR3
SCHEMBL3728983 1.00 LMNA (0.58) LMNAGAAKDM4EHRH1CCR3
SCHEMBL627928 1.00 LMNA (0.58) LMNAGAAKDM4EHRH1CCR3
SCHEMBL890204 0.88 DPP4 (0.44) LMNAGAAKDM4ETSHRALDH1A1
SCHEMBL13154902 0.88 DPP4 (0.44) LMNAGAAKDM4ETSHRALDH1A1
SCHEMBL890201 0.88 DPP4 (0.44) LMNAGAAKDM4ETSHRALDH1A1
SCHEMBL12174930 0.88 DPP4 (0.44) LMNAGAAKDM4ETSHRALDH1A1
SCHEMBL12292181 0.88 DPP4 (0.44) LMNAGAAKDM4ETSHRALDH1A1
SCHEMBL13154957 0.88 DPP4 (0.44) LMNAGAAKDM4ETSHRALDH1A1
SCHEMBL29038675 0.86 LMNA (0.57) LMNAGAAKDM4EHRH1CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1873208-B2 CURABLE COMPOSITION AND CURED ARTICLE EXCELLENT IN TRANSPARENCY KANEKA CORP (JP) 2024-10-09 EP disclosed
EP-1873208-B1 CURABLE COMPOSITION AND CURED ARTICLE EXCELLENT IN TRANSPARENCY KANEKA CORP (JP) 2017-12-06 EP disclosed
US-9278922-B2 Anti-viral compounds ABBVIE INC. (US) 2016-03-08 US disclosed
EP-2419404-B1 ANTI-VIRAL COMPOUNDS ABBVIE INC (US) 2015-11-04 EP disclosed
US-8759435-B2 Curable composition and cured article excellent in transparency KANEKA CORPORATION (JP) 2014-06-24 US disclosed
EP-1832626-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2012-06-13 EP disclosed
EP-2419404-A1 ANTI-VIRAL COMPOUNDS Abbott Laboratories (US) 2012-02-22 EP disclosed
WO-2010120935-A1 ANTI-VIRAL COMPOUNDS ABBOTT LABORATORIES (US) 2010-10-21 WO disclosed
US-20100267634-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2010-10-21 US disclosed
US-7781525-B2 Curable composition KANEKA CORPORATION (JP) 2010-08-24 US disclosed
US-20090087635-A1 Curable Composition and Cured Article Excellent in Transparency KANEKA CORPORATION (JP) 2009-04-02 US disclosed
US-20080188624-A1 Curable Composition KANEKA CORPORATION (JP) 2008-08-07 US disclosed
EP-1873208-A1 CURABLE COMPOSITION AND CURED ARTICLE EXCELLENT IN TRANSPARENCY Kaneka Corporation (JP) 2008-01-02 EP disclosed
EP-1832626-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2007-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267634-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS LMNA 3118/4885GAA 223/4885KDM4E 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.