Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063978 | 0.87 | TSHR (0.48) | TSHRHCAR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2098739 | 0.80 | TSHR (0.42) | TSHRHCAR2KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29090138 | 0.78 | TSHR (0.46) | TSHRHCAR2KMT2AMEN1LMNA | |
| SCHEMBL26939576 | 0.78 | ELANE (0.34) | TSHRELANEALDH1A1CYP2C19CYP2D6 | |
| SCHEMBL28145028 | 0.78 | TSHR (0.40) | TSHRHCAR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3371032 | 0.78 | MAPT (0.35) | TSHRELANECYP2C19MAPTNPSR1 | |
| SCHEMBL2478389 | 0.76 | TSHR (0.48) | TSHRHCAR2KMT2AMEN1ELANE | |
| SCHEMBL4675881 | 0.74 | TSHR (0.46) | TSHRHCAR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4675760 | 0.74 | TSHR (0.46) | TSHRHCAR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL448528 | 0.74 | TSHR (0.46) | TSHRHCAR2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700654-A | Copolyester for weather-resistant coating and preparation method and application thereof | 中瀚新材料科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-115449900-B | Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer | 浙江奥首材料科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-115449900-A | Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer | 浙江奥首材料科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| WO-2012021446-A2 | PROCESS FOR PREPARING ALISKIREN AND ITS INTERMEDIATES | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-02-16 | — | — | WO | claimed |
| CN-117700654-A | Copolyester for weather-resistant coating and preparation method and application thereof | 中瀚新材料科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-20230400766-A1 | ONIUM SALT, RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-14 | — | — | US | disclosed |
| CN-115449900-B | Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer | 浙江奥首材料科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-115449900-A | Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer | 浙江奥首材料科技有限公司 | 2022-12-09 | — | — | CN | disclosed |
| EP-2571862-B1 | PRODRUG OF TRIAZOLONE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2014-04-16 | — | — | EP | disclosed |
| US-8436009-B2 | Prodrug of triazolone compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| EP-2571862-A1 | PRODRUG OF TRIAZOLONE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-20130053563-A1 | PRODRUG OF TRIAZOLONE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-28 | — | — | US | disclosed |
| WO-2012021446-A2 | PROCESS FOR PREPARING ALISKIREN AND ITS INTERMEDIATES | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011145747-A1 | PRODRUG OF TRIAZOLONE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-24 | — | — | WO | disclosed |
| US-4824981-A | REACTING MALONATES WITH TRIALKYLSILANES, ALKALI METAL AND DIALKYLMALONIC ACID; PURITY | DOW CORNING CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0298363-A2 | A process to produce silyl ketene acetals | DOW CORNING CORPORATION (US) | 1989-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053563-A1 | PRODRUG OF TRIAZOLONE COMPOUND | F7, TFPI, TFPI2 | TSHR 1050/4885HCAR2 1592/4885KMT2A 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.