Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500363 | 0.67 | CA12 (0.46) | PIK3R1PIK3CASMN1; SMN2MAPTHPGD | |
| SCHEMBL28024737 | 0.63 | PRKDC (0.51) | JAK3PIK3R1PIK3CAHSD17B10ALDH1A1 | |
| Fluoride SCHEMBL27679532 | 0.62 | BRD4 (0.31) | — | |
| SCHEMBL22150604 | 0.61 | PIK3CA (0.49) | PIK3CAALDH1A1MAPTKMT2AEP300 | |
| SCHEMBL6227943 | 0.61 | CRBN (0.41) | HSD17B10ALDH1A1KMT2ATSHRGAA | |
| SCHEMBL9443401 | 0.61 | CRBN (0.41) | — | |
| SCHEMBL942469 | 0.60 | PIK3CB (0.51) | JAK3PIK3R1PIK3CASMN1; SMN2KMT2A | |
| SCHEMBL17906986 | 0.59 | PRKDC (0.42) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL438291 | 0.59 | — | — | |
| SCHEMBL3763 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994133-A | Morpholino nucleoside monomer full-flow synthesis process based on unprotected ring expansion strategy | 浙江大学 | 2024-11-22 | — | — | CN | disclosed |
| EP-0973886-B1 | METHOD AND CONJUGATE FOR TREATING HELICOBACTER PYLORI INFECTIONS | AVI BIOPHARM INC (US) | 2005-03-23 | — | — | EP | disclosed |
| US-6124271-A | ANTISENSE CONJUGATE STABLE TO STOMACH ENVIRONMENT AND COMPOSED OF AN UPTAKE FACILITATING TRANSPORT MOIETY CONJUGATED TO A NUCLEASE-RESISTANT ANTISENSE OLIGOMER WHICH BASE-SPECIFICALLY BINDS TO H. PYLORI MRNA TRANSCRIPT | AVI BIOPHARMA, INC. | 2000-09-26 | — | — | US | disclosed |
| US-6030941-A | FOR DELIVERY OF DRUGS AND OTHER COMPOUNDS ACROSS LIPID LAYERS | AVI BIOPHARMA, INC. (US) | 2000-02-29 | — | — | US | disclosed |