Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350084 | 0.93 | MTOR (0.56) | MTORNAMPTTRPV1CHRNA7CNR1 | |
| SCHEMBL4353993 | 0.85 | MTOR (0.67) | MTORMAPTNAMPTTRPV1CNR1 | |
| SCHEMBL4349059 | 0.84 | GRIK1 (0.63) | MTORMAPTTRPV1CHRNA7CNR1 | |
| SCHEMBL4351477 | 0.80 | MAPT (0.55) | MAPTHTTMEN1KMT2A | |
| SCHEMBL6229030 | 0.79 | MTOR (0.43) | MTORMAPTNAMPTCNR1HTT | |
| SCHEMBL3671992 | 0.79 | CHRNA7 (0.72) | MAPTTRPV1CHRNA7MEN1KMT2A | |
| SCHEMBL4348962 | 0.79 | MTOR (0.50) | MTORNAMPTTRPV1CHRNA7CNR1 | |
| SCHEMBL4345888 | 0.79 | P2RY1 (0.56) | MAPTTRPV1GRIK1RAB9AHTT | |
| SCHEMBL4357690 | 0.78 | CHRNA7 (0.64) | MTORNAMPTTRPV1CHRNA7CNR1 | |
| SCHEMBL4357504 | 0.78 | TRPV1 (0.61) | MTORMAPTNAMPTTRPV1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |