Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 13/20 | 0.66 |
| ▸ | HRH1 | P35367 | 13/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 13/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flezelastine SCHEMBL29687099 | 1.00 | ADRA1A (0.66) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| Flezelastine SCHEMBL219748 | 0.99 | ADRA1A (0.65) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL10372558 | 0.91 | ADRA1A (0.79) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL10557080 | 0.90 | ADRA1A (0.64) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL10766274 | 0.86 | ADRA1A (0.65) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL2615138 | 0.85 | HRH1 (0.81) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL2615137 | 0.85 | HRH1 (0.81) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL10557572 | 0.83 | ADRA1A (0.80) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL10375081 | 0.82 | ADRA1A (0.75) | ADRA1AHRH1ADRA1BHRH3ADRA2A | |
| SCHEMBL10555618 | 0.81 | ADRA1A (0.65) | ADRA1AHRH1ADRA1BHRH3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7488 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116861-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-04-30 | — | — | US | claimed |
| US-12522572-B2 | Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-01-13 | — | — | US | claimed |
| US-20240343697-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2024-10-17 | — | — | US | claimed |
| US-11345956-B2 | Methods and compositions related to prostate cancer therapeutics | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-05-31 | — | — | US | claimed |
| US-11207289-B2 | Use of benzofuran lignans to induce IL-25 expression and suppress mammary tumor metastasis | ACADEMIA SINICA (TW) | 2021-12-28 | — | — | US | claimed |
| US-10953073-B2 | XTEN conjugate compositions and methods of making same | AMUNIX PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | claimed |
| US-20210060040-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2021-03-04 | — | — | US | claimed |
| EP-3191114-B1 | OCCIDIOFUNGIN FORMULATIONS AND USES THEREOF | UNIV MISSISSIPPI STATE (US) | 2021-03-03 | — | — | EP | claimed |
| US-20200289454-A1 | USE OF BENZOFURAN LIGNANS TO INDUCE IL-25 EXPRESSION AND SUPPRESS MAMMARY TUMOR METASTASIS | Yang, Ning-Sun (TW) | 2020-09-17 | — | — | US | claimed |
| US-20200270362-A1 | MSLN TARGETING TRISPECIFIC PROTEINS AND METHODS OF USE | HARPOON THERAPEUTICS, INC. | 2020-08-27 | — | — | US | claimed |
| US-20040092583-A1 | Treatment for inhibiting neoplastic lesions | SHANAHAN-PRENDERGAST ELIZABETH (IE) | 2004-05-13 | — | — | US | claimed |
| EP-1351678-A2 | TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS | Shanahan-Prendergast, Elizabeth (IE) | 2003-10-15 | — | — | EP | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| WO-2002053138-A2 | TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS | SHANAHAN-PRENDERGAST ELISABETH (IE) | 2002-07-11 | — | — | WO | claimed |
| EP-0888127-B1 | COMBINATIONS HAVING IMMUNOSUPPRESSIVE EFFECTS, CONTAINING CYCLOOXYGENASE-2-INHIBITORS AND 5-LIPOXYGENASE INHIBITORS | SEARLE & CO (US) | 2001-12-12 | — | — | EP | claimed |
| EP-0659744-B1 | Process of preparation of hexahydroazepinones and hexahydroazepinoles | ASTA MEDICA AG (DE) | 2001-02-28 | — | — | EP | claimed |
| US-5760221-A | Method for the preparation of hexahydroazepinones and hexahydroazepinoles | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | claimed |
| EP-0590551-B1 | New therapeutic uses of phthalazinone-derivatives | ASTA MEDICA AG (DE) | 1996-10-30 | — | — | EP | claimed |
| US-5556856-A | ANITARRHYTHMIA, ANALGESICS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | claimed |
| US-5536444-A | Compressed-gas packages using polyoxyethylene glyceryl fatty-acid esters as suspension stabilizers and valve lubricants | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-07-16 | — | — | US | claimed |