Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | IDE | P14735 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6204777 | 0.99 | MEN1 (0.71) | MEN1KMT2AIDESMN1; SMN2KDM4E | |
| SCHEMBL6205541 | 0.82 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNANPC1 | |
| SCHEMBL7851349 | 0.78 | IDE (0.90) | MEN1KMT2AIDESMN1; SMN2 | |
| SCHEMBL7285112 | 0.78 | KMT2A (0.67) | MEN1KMT2AIDESMN1; SMN2LMNA | |
| SCHEMBL4519037 | 0.78 | MEN1 (0.59) | MEN1KMT2AIDESMN1; SMN2KDM4E | |
| SCHEMBL10856486 | 0.77 | MEN1 (0.70) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL13894536 | 0.77 | CFTR (0.58) | LMNAL3MBTL1 | |
| SCHEMBL34468767 | 0.77 | KDM4E (0.67) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL11010135 | 0.77 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL10655218 | 0.76 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |