Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6228655 | 0.98 | KMT2A (0.49) | KMT2AMEN1MAPK1MAPTTDP1 | |
| Bromide SCHEMBL3884586 | 0.76 | KMT2A (0.53) | KMT2AMEN1MAPK1MAPTTDP1 | |
| Bromide SCHEMBL6230012 | 0.74 | KMT2A (0.47) | KMT2AMEN1MAPK1MAPTTDP1 | |
| SCHEMBL764729 | 0.70 | KMT2A (0.57) | KMT2AMEN1MAPK1MAPTTDP1 | |
| SCHEMBL765905 | 0.69 | KDM4E (0.76) | KMT2AMEN1MAPK1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL2527501 | 0.68 | KMT2A (0.73) | KMT2AMEN1MAPK1MAPTTDP1 | |
| Ammonia Solution, Strong SCHEMBL28760030 | 0.68 | KDM4E (0.73) | KMT2AMEN1MAPK1MAPTTDP1 | |
| Bromide SCHEMBL698678 | 0.68 | KDM4E (0.79) | KMT2AMEN1MAPK1MAPTTDP1 | |
| Dibenzoylmethane SCHEMBL39582 | 0.67 | MEN1 (1.00) | KMT2AMEN1MAPK1MAPTTDP1 | |
| SCHEMBL719034 | 0.67 | NR4A2 (0.85) | KMT2AMEN1MAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098647-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING TISSUE ISCHEMIA | LONG ISLAND JEWISH RES INST (US) | 2005-03-23 | — | — | EP | claimed |