SCHEMBL6229252

SCHEMBL6229252

Cc1cccc(C(c2ccccc2)c2cccc(C)c2C)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.43
ESR1 P03372 1/20 0.40
ADRA2A P08913 5/20 0.40
ADRA2B P18089 5/20 0.40
ADRA2C P18825 4/20 0.40
ADRA1A P35348 4/20 0.40
ADRA1B P35368 3/20 0.40
CYP2D6 P10635 3/20 0.40
ADRA1D P25100 2/20 0.40
KCNH2 Q12809 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C9 P11712 2/20 0.40
TSHR P16473 2/20 0.40
CYP2C19 P33261 2/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
SLC6A2 P23975 3/20 0.39
HTR7 P34969 1/20 0.39
TRPA1 O75762 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6225155 0.96 ACP3 (0.44) ACP3ESR1ADRA2AADRA2BADRA2C
SCHEMBL11410676 0.96 ACP3 (0.43) ACP3ESR1ADRA2AADRA2BADRA2C
SCHEMBL31489175 0.85 ACP3 (0.40) ACP3ESR1ADRA2AADRA2BADRA2C
SCHEMBL5270216 0.84 ACP3 (0.52) ACP3ESR1ADRA2AADRA2BADRA1A
SCHEMBL629239 0.84 TRPA1 (0.46) ESR1ADRA2AADRA2BADRA2CADRA1A
SCHEMBL29358402 0.83 ADRA2A (0.47) ACP3ESR1ADRA2AADRA2BADRA2C
SCHEMBL115911 0.83 ADRA2A (0.47) ACP3ESR1ADRA2AADRA2BADRA2C
SCHEMBL3648824 0.82 ESR1 (0.48) ACP3ESR1ADRA2AADRA2BADRA2C
SCHEMBL2422170 0.79 ACP3 (0.52) ACP3ESR1ADRA2AADRA2BADRA1A
SCHEMBL22819913 0.79 GAA (0.44) ACP3TSHRCYP1A2SLC6A2SCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6908673-B2 Cable with recyclable covering PIRELLI CAVI E SISTEMI S.P.A. (IT) 2005-06-21 US claimed
EP-1295301-B1 CABLE WITH RECYCLABLE COVERING PIRELLI & C SPA (IT) 2004-04-14 EP claimed
US-20030138628-A1 Cable with recyclable covering PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2003-07-24 US claimed
EP-1295301-A1 CABLE WITH RECYCLABLE COVERING PIRELLI S.p.A. (IT) 2003-03-26 EP claimed
WO-2002003398-A1 CABLE WITH RECYCLABLE COVERING PIRELLI CAVI E SISTEMI SPA (IT) 2002-01-10 WO claimed
US-4181328-A Recording element FUJI PHOTO FILM CO., LTD. (JP) 1980-01-01 US claimed
EP-3883522-B1 USE OF A POLYETHER-MODIFIED POLYDIMETHYL SILOXANE FOR REDUCING THE STICKINESS OF A DENTAL IMPRESSION COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-01-08 EP disclosed
US-11872292-B2 Cationically and radiation curable composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-16 US disclosed
EP-3319580-B1 KIT OF PARTS CONTAINING A CATIONICALLY HARDENABLE COMPOSITION AND USE AS DENTAL RETRACTION MATERIAL 3M INNOVATIVE PROPERTIES CO (US) 2022-04-06 EP disclosed
US-6908673-B2 Cable with recyclable covering PIRELLI CAVI E SISTEMI S.P.A. (IT) 2005-06-21 US disclosed
EP-1295301-B1 CABLE WITH RECYCLABLE COVERING PIRELLI & C SPA (IT) 2004-04-14 EP disclosed
US-20030138628-A1 Cable with recyclable covering PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2003-07-24 US disclosed
EP-1295301-A1 CABLE WITH RECYCLABLE COVERING PIRELLI S.p.A. (IT) 2003-03-26 EP disclosed
WO-2002003398-A1 CABLE WITH RECYCLABLE COVERING PIRELLI CAVI E SISTEMI SPA (IT) 2002-01-10 WO disclosed
US-5601755-A LIQUID MIXTURES WITH BENZYLTOLUENES, BENZYLXYLENES AND THEIR METHYL DERIVATIVES HAVING HIGH BREAKDOWN VOLTAGE ATOCHEM (FR) 1997-02-11 US disclosed
EP-0446086-B1 Composition comprising methyl and benzyl derivatives of diphenylmethane and its use as dielectricum ATOCHEM ELF SA (FR) 1993-12-08 EP disclosed
EP-0446086-A1 Composition comprising methyl and benzyl derivatives of diphenylmethane and its use as dielectricum ELF ATOCHEM S.A. (FR) 1991-09-11 EP disclosed
US-4181328-A Recording element FUJI PHOTO FILM CO., LTD. (JP) 1980-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11872292-B2 Cationically and radiation curable composition RAD51, SMARCA1, SMARCA4 ACP3 2850/4885ESR1 2273/4885ADRA2A 2900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.