Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23829890 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL11788958 | 0.76 | HSD17B10 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL11788952 | 0.76 | HSD17B10 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL8050895 | 0.74 | HCAR2 (0.43) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL8038362 | 0.74 | HCAR2 (0.43) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL530968 | 0.73 | — | — | |
| SCHEMBL530967 | 0.73 | — | — | |
| SCHEMBL13459843 | 0.73 | — | — | |
| SCHEMBL19949751 | 0.72 | — | — | |
| SCHEMBL27210441 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021403-B1 | 2,3-DIOXABICYCLO 3.3.1]NONANE DERIVATIVES AND ANTIMALARIAL PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RES & DEV (IL) | 2005-04-20 | — | — | EP | claimed |
| US-6166065-A | 2,3-dioxabicyclo[3.3.1]nonane derivatives and antimalarial pharmaceutical compositions comprising them | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2000-12-26 | — | — | US | claimed |
| EP-1021403-A2 | 2,3-DIOXABICYCLO 3.3.1]NONANE DERIVATIVES AND ANTIMALARIAL PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2000-07-26 | — | — | EP | claimed |
| WO-1999012900-A2 | 2,3-DIOXABICYCLO[3.3.1]NONANE DERIVATIVES AND ANTIMALARIAL PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1999-03-18 | — | — | WO | claimed |
| EP-1021403-B1 | 2,3-DIOXABICYCLO 3.3.1]NONANE DERIVATIVES AND ANTIMALARIAL PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RES & DEV (IL) | 2005-04-20 | — | — | EP | disclosed |
| US-6166065-A | 2,3-dioxabicyclo[3.3.1]nonane derivatives and antimalarial pharmaceutical compositions comprising them | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2000-12-26 | — | — | US | disclosed |
| EP-1021403-A2 | 2,3-DIOXABICYCLO 3.3.1]NONANE DERIVATIVES AND ANTIMALARIAL PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999012900-A2 | 2,3-DIOXABICYCLO[3.3.1]NONANE DERIVATIVES AND ANTIMALARIAL PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1999-03-18 | — | — | WO | disclosed |