Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050895 | 1.00 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL9588257 | 0.81 | — | — | |
| SCHEMBL8983231 | 0.81 | — | — | |
| SCHEMBL8822877 | 0.81 | — | — | |
| SCHEMBL11126166 | 0.75 | NPSR1 (0.52) | HCAR2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL27796438 | 0.74 | MGAM (0.37) | HCAR2KEAP1NFE2L2TSHRKDM4E | |
| SCHEMBL23829890 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1KDM4E | |
| SCHEMBL6229863 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL14225485 | 0.73 | HCAR2 (0.53) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL273328 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758648-B1 | Substituted 4H-pyrans with a modulating effect on calcium channels | BAYER AG (DE) | 2000-03-15 | — | — | EP | disclosed |
| US-6011119-A | RESIN COMPOSITION SHOWS EXCELLENT CHARGING CHARACTERISTICS WITHOUT A CHARGE CONTROL AGENT; HIGH AND LOW MOLECULAR WEIGHT ADDITION POLYMERS AT LEAST ONE OF WHICH IS FROM AN UNSATURATED ANHYDRIDE AND AN ACRYLOYLOXYALKYL DICARBOXYLIC ACID ESTER | MITSUI CHEMICALS, INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| US-5760073-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |
| EP-0758648-A1 | Substituted 4H-pyrans with a modulating effect on calcium channels | BAYER AG (DE) | 1997-02-19 | — | — | EP | disclosed |
| EP-0756208-A1 | Resin composition for electrophotographic toner, and toner comprising it | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0043088-B1 | PROCESS FOR THE PRODUCTION OF ALKYL ESTERS OF ACETOACTIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-18 | — | — | EP | disclosed |