Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | PRKACG | P22612 | 1/20 | 0.30 |
| ▸ | PRKACB | P22694 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335690 | 0.69 | PKM (0.38) | PKMLPAR1PRKACAPRKACGPRKACB | |
| SCHEMBL8008525 | 0.65 | PKM (0.32) | PKMPRKACAPRKACGPRKACB | |
| SCHEMBL5823747 | 0.63 | PKM (0.49) | PKMLPAR1 | |
| SCHEMBL4758516 | 0.62 | PRKACA (0.42) | PRKACAPRKACGPRKACB | |
| SCHEMBL7335692 | 0.60 | PRKACA (0.38) | PRKACAPRKACGPRKACB | |
| SCHEMBL810891 | 0.59 | KDM4E (0.44) | PKM | |
| SCHEMBL31277867 | 0.59 | PRKACA (0.37) | PRKACAPRKACGPRKACB | |
| SCHEMBL8645691 | 0.57 | PRKACA (0.43) | PRKACAPRKACGPRKACB | |
| SCHEMBL31278209 | 0.57 | PRKACA (0.43) | PRKACAPRKACGPRKACB | |
| SCHEMBL4758514 | 0.56 | PKM (0.72) | PKMLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499614-A4 | ADENOSINE A3 RECEPTOR MODULATORS | KING PHARMACEUTICALS RES & DEV (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1499614-A1 | ADENOSINE A3 RECEPTOR MODULATORS | King Pharmaceuticals Research and Development Inc. (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003095457-A1 | ADENOSINE A3 RECEPTOR MODULATORS | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2003-11-20 | — | — | WO | disclosed |