Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823747 | 0.73 | PKM (0.49) | PKMLPAR1 | |
| SCHEMBL4758516 | 0.71 | PRKACA (0.42) | PRKACAPRKACGPRKACB | |
| SCHEMBL7335692 | 0.71 | PRKACA (0.38) | PRKACAPRKACGPRKACB | |
| SCHEMBL6229864 | 0.69 | PKM (0.38) | PKMPRKACAPRKACGPRKACBLPAR1 | |
| SCHEMBL8003196 | 0.69 | PKM (0.36) | PKM | |
| SCHEMBL8008525 | 0.68 | PKM (0.32) | PKMPRKACAPRKACGPRKACB | |
| SCHEMBL4759855 | 0.67 | KDM4E (0.41) | PKMLPAR1 | |
| SCHEMBL4759856 | 0.65 | PRKACA (0.41) | PRKACAPRKACGPRKACB | |
| SCHEMBL55228 | 0.64 | KDM4E (0.44) | PKMLPAR1 | |
| SCHEMBL25432010 | 0.58 | KMT2A (0.42) | PKMLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015231-A1 | ADENOSINE A3 RECEPTOR MODULATORS | MEDCO RESEARCH INC. (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1995001356-A1 | 1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE HETEROCYCLIC ANALOGUES HAVING ANTAGONISTIC ACTIVITY ON ADENOSINE A2 RECEPTOR | SCHERING-PLOUGH S.P.A. (IT) | 1995-01-12 | — | — | WO | disclosed |