Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19958406 | 0.81 | MAOA (0.43) | MAOAPOLBMAPTMEN1KMT2A | |
| SCHEMBL4732207 | 0.78 | MAOA (0.54) | MAOAPOLBALDH1A1MAPTHTT | |
| SCHEMBL18631368 | 0.75 | MAOA (0.54) | MAOAPOLBALDH1A1MAPTHTT | |
| SCHEMBL29844652 | 0.74 | MAOA (0.54) | MAOAMEN1KMT2AKDM4ECA12 | |
| SCHEMBL29958223 | 0.74 | MAOA (0.54) | MAOAMEN1KMT2AKDM4ECA12 | |
| SCHEMBL290638 | 0.74 | MAOA (0.54) | MAOAMEN1KMT2AKDM4ECA12 | |
| Water SCHEMBL7420168 | 0.72 | MAOA (0.53) | MAOAMEN1KMT2AKDM4ECA12 | |
| SCHEMBL6228411 | 0.71 | MAOA (0.41) | MAOAMAPTKDM4E | |
| SCHEMBL19958407 | 0.68 | MAOA (0.43) | MAOAPOLBMAPTMEN1KMT2A | |
| SCHEMBL4735128 | 0.68 | MAOA (0.40) | MAOAPOLBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261298-A1 | Methods of treating conditions associated with an Edg-7 receptor | MANIV ENERGY CAPITAL | 2005-11-24 | — | — | US | disclosed |
| EP-1513522-A2 | METHODS OF TREATING CONDITIONS ASSOCIATED WITH AN EDG RECEPTOR | SRI INTERNATIONAL (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20040167165-A1 | Methods of treating conditions associated with an Edg-7 receptor | MANIV ENERGY CAPITAL | 2004-08-26 | — | — | US | disclosed |
| WO-2003062392-A2 | METHODS OF TREATING CONDITIONS ASSOCIATED WITH AN EDG RECEPTOR | CERETEK LLC (US) | 2003-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167165-A1 | Methods of treating conditions associated with an Edg-7 receptor | EDNRA, EDNRB, ESRRG | MAOA 1592/4885POLB 4484/4885ALDH1A1 2718/4885 |
| US-20050261298-A1 | Methods of treating conditions associated with an Edg-7 receptor | EDNRA, EDNRB, ESRRG | MAOA 1592/4885POLB 4484/4885ALDH1A1 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.