Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235487 | 0.88 | TP53 (0.43) | L3MBTL1SLC2A1NPY5RGAAPOLB | |
| SCHEMBL6231898 | 0.88 | TP53 (0.43) | L3MBTL1SLC2A1NPY5RGAAPOLB | |
| SCHEMBL6238037 | 0.86 | NPY5R (0.60) | SLC2A1NPY5RPOLBMEN1KMT2A | |
| SCHEMBL6233063 | 0.85 | SLC2A1 (0.71) | SLC2A1NPY5RGAAMEN1KMT2A | |
| SCHEMBL6234079 | 0.85 | SLC2A1 (0.50) | SLC2A1NPY5RPOLBMEN1KMT2A | |
| SCHEMBL6233775 | 0.85 | SLC2A1 (0.50) | SLC2A1NPY5RGAAPOLBMEN1 | |
| SCHEMBL6235222 | 0.83 | GAA (0.47) | L3MBTL1SLC2A1NPY5RGAAPOLB | |
| SCHEMBL6231257 | 0.83 | MEN1 (0.42) | L3MBTL1SLC2A1NPY5RGAAPOLB | |
| SCHEMBL6233225 | 0.82 | POLB (0.51) | L3MBTL1SLC2A1NPY5RPOLBMEN1 | |
| SCHEMBL6088380 | 0.82 | NPY5R (0.54) | SLC2A1NPY5RPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430030-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | disclosed |