Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235684 | 0.88 | TP53 (0.43) | NPY5RKDM1AMAPK14MAPK13MAPK12 | |
| SCHEMBL6238037 | 0.86 | NPY5R (0.60) | SLC2A1NPY5RPOLA1MEN1KMT2A | |
| SCHEMBL6230099 | 0.85 | L3MBTL1 (0.51) | SLC2A1NPY5RPOLA1MEN1KMT2A | |
| SCHEMBL6233063 | 0.85 | SLC2A1 (0.71) | SLC2A1NPY5RMAPK14MAPK13MAPK12 | |
| SCHEMBL6234079 | 0.85 | SLC2A1 (0.50) | SLC2A1NPY5RMEN1KMT2ANPC1 | |
| SCHEMBL6234312 | 0.85 | SMN1; SMN2 (0.65) | SLC2A1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6233025 | 0.83 | MAPT (0.42) | SLC2A1NPY5RMAPK14MAPK13MAPK12 | |
| SCHEMBL6233510 | 0.83 | MAPK14 (0.41) | NPY5RMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6233225 | 0.82 | POLB (0.51) | SLC2A1NPY5RMAPK14MEN1KMT2A | |
| SCHEMBL6091625 | 0.79 | NPY5R (0.57) | SLC2A1NPY5RPOLA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430030-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | disclosed |