Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229818 | 0.89 | CCNC (0.48) | TP53SMN1; SMN2MAPTGAAMEN1 | |
| SCHEMBL6230099 | 0.88 | L3MBTL1 (0.51) | TP53SMN1; SMN2MAPTGAAPOLB | |
| SCHEMBL6238255 | 0.88 | NPY5R (0.51) | TP53SMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL6231898 | 0.87 | TP53 (0.43) | TP53SMN1; SMN2MAPTGAAPOLB | |
| SCHEMBL6087570 | 0.81 | TP53 (0.50) | TP53SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL6088381 | 0.81 | SMN1; SMN2 (0.52) | TP53SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL6231257 | 0.80 | MEN1 (0.42) | TP53SMN1; SMN2MAPTGAAPOLB | |
| SCHEMBL6234079 | 0.78 | SLC2A1 (0.50) | TP53SMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL6231629 | 0.78 | TP53 (0.43) | TP53SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6235222 | 0.76 | GAA (0.47) | TP53SMN1; SMN2MAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430030-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | disclosed |