Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.43 |
| ▸ | PGR | P06401 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226237 | 0.87 | MCL1 (0.35) | NR3C1NR3C2PGR | |
| SCHEMBL6226624 | 0.84 | NR3C1 (0.39) | NR3C1NR3C2PGR | |
| SCHEMBL1933238 | 0.78 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL6226557 | 0.77 | NR3C1 (0.56) | NR3C1NR3C2PGR | |
| SCHEMBL5381739 | 0.77 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL4437966 | 0.76 | NR3C1 (0.42) | NR3C1NR3C2PGR | |
| SCHEMBL292879 | 0.75 | NR3C1 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL3652175 | 0.75 | NR3C1 (0.44) | NR3C1NR3C2PGR | |
| SCHEMBL6225165 | 0.74 | NR3C1 (0.50) | NR3C1NR3C2PGR | |
| SCHEMBL6230117 | 0.74 | NR3C1 (0.38) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511716-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-03-09 | — | — | EP | claimed |
| WO-2003101932-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-11 | — | — | WO | claimed |
| EP-1511716-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003101932-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-11 | — | — | WO | disclosed |