Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230116 | 0.87 | NR3C1 (0.43) | NR3C1PGRNR3C2 | |
| SCHEMBL4432727 | 0.75 | NR3C1 (0.36) | NR3C1PGRNR3C2 | |
| SCHEMBL5389781 | 0.75 | NR3C1 (0.39) | NR3C1PGRNR3C2 | |
| SCHEMBL5518605 | 0.74 | NR3C1 (0.52) | NR3C1PGRNR3C2 | |
| SCHEMBL6226239 | 0.73 | MCL1 (0.32) | MCL1P2RX7 | |
| SCHEMBL6226624 | 0.71 | NR3C1 (0.39) | NR3C1PGRNR3C2 | |
| SCHEMBL24018795 | 0.71 | KCNH2 (0.37) | DDR1RIPK1KMT2A | |
| SCHEMBL22957721 | 0.66 | SLC6A4 (0.48) | DDR1RIPK1 | |
| SCHEMBL3649792 | 0.66 | NR3C1 (0.45) | NR3C1PGRNR3C2 | |
| SCHEMBL5523891 | 0.65 | NR3C1 (0.34) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511716-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-03-09 | — | — | EP | claimed |
| WO-2003101932-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-11 | — | — | WO | claimed |