Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 9/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624084 | 0.88 | F2RL3 (0.45) | PIM1F2RL3ACP1IRAK4 | |
| SCHEMBL627162 | 0.87 | F2RL3 (0.44) | ACKR3PIM1F2RL3ACP1IRAK4 | |
| SCHEMBL624533 | 0.86 | PIM1 (0.53) | PIM1 | |
| SCHEMBL2253772 | 0.85 | ACP1 (0.52) | PIM1F2RL3ACP1 | |
| SCHEMBL623873 | 0.85 | IDH1 (0.44) | PIM1ABHD6DAGLA | |
| SCHEMBL625517 | 0.84 | PIM1 (0.47) | PIM1F2RL3ACP1 | |
| SCHEMBL1944702 | 0.84 | PIM1 (0.55) | PIM1F2RL3ACP1 | |
| SCHEMBL623028 | 0.84 | ACKR3 (0.54) | ACKR3PIM1 | |
| SCHEMBL624454 | 0.83 | PIM1 (0.45) | PIM1ABHD6DAGLAF2RL3 | |
| SCHEMBL625496 | 0.82 | PIM1 (0.39) | PIM1ABHD6DAGLAF2RL3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |