Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 8/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253772 | 0.91 | ACP1 (0.52) | PIM1ACP1F2RL3PIM3PIM2 | |
| SCHEMBL624084 | 0.90 | F2RL3 (0.45) | PIM1ACP1F2RL3KCNH2PIM3 | |
| SCHEMBL1944702 | 0.90 | PIM1 (0.55) | PIM1ACP1F2RL3PIM3PIM2 | |
| SCHEMBL627162 | 0.90 | F2RL3 (0.44) | PIM1ACP1F2RL3PIM3PIM2 | |
| SCHEMBL1944572 | 0.86 | SCN9A (0.41) | PIM1ACP1F2RL3SYK | |
| SCHEMBL623029 | 0.84 | ACKR3 (0.51) | PIM1ACP1F2RL3 | |
| SCHEMBL625504 | 0.83 | PIM1 (0.56) | PIM1F2RL3KCNH2PIM3PIM2 | |
| SCHEMBL625516 | 0.82 | PIM1 (0.57) | PIM1KCNH2PIM3PIM2GAK | |
| SCHEMBL1944086 | 0.82 | F2RL3 (0.51) | PIM1F2RL3SYK | |
| SCHEMBL1945213 | 0.82 | F2RL3 (0.46) | PIM1ACP1F2RL3PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |