SCHEMBL623036

SCHEMBL623036

O=C(Nc1ncc(F)s1)C(OC1CCCC1)c1ccc(S(=O)(=O)N2CCCC2)cc1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCK P35557 18/20 0.79
FFAR2 O15552 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185118 0.92 GCK (0.90) GCK
SCHEMBL185059 0.88 GCK (1.00) GCK
SCHEMBL625197 0.82 GCK (0.71) GCK
SCHEMBL625210 0.81 GCK (0.70) GCK
SCHEMBL184841 0.80 GCK (0.75) GCK
SCHEMBL628093 0.80 ALDH1A1 (0.59) GCK
SCHEMBL11972156 0.80 GCK (0.66) GCK
SCHEMBL184635 0.80 GCK (0.75) GCK
SCHEMBL623635 0.80 GCK (0.60) GCK
SCHEMBL626401 0.79 GCK (0.56) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO claimed