Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GCK | P35557 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627708 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HPGDHSD17B10USP2 | |
| SCHEMBL624684 | 0.80 | GCK (0.54) | ALDH1A1SMN1; SMN2HPGDHSD17B10USP2 | |
| SCHEMBL623036 | 0.80 | GCK (0.79) | GCK | |
| SCHEMBL623635 | 0.80 | GCK (0.60) | ALDH1A1SMN1; SMN2HPGDHSD17B10USP2 | |
| SCHEMBL626401 | 0.79 | GCK (0.56) | ALDH1A1SMN1; SMN2HPGDHSD17B10USP2 | |
| SCHEMBL185118 | 0.77 | GCK (0.90) | GCK | |
| SCHEMBL184720 | 0.76 | GCK (0.91) | ALDH1A1SMN1; SMN2HPGDHSD17B10USP2 | |
| SCHEMBL184038 | 0.76 | GCK (0.68) | ALDH1A1SMN1; SMN2GCKMAPK1MAPT | |
| SCHEMBL626280 | 0.76 | GCK (0.60) | GCK | |
| SCHEMBL11971963 | 0.74 | GCK (0.77) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | claimed |