Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759953 | 0.90 | ALDH1A1 (0.48) | ALDH1A1NPSR1TP53GRIN2BSMN1; SMN2 | |
| SCHEMBL10759948 | 0.90 | ALDH1A1 (0.48) | ALDH1A1NPSR1TP53GRIN2BSMN1; SMN2 | |
| SCHEMBL7875386 | 0.88 | NPSR1 (0.53) | ALDH1A1NPSR1TP53GRIN2BPKM | |
| SCHEMBL1056362 | 0.87 | PREP (0.60) | ALDH1A1NPSR1TP53SMN1; SMN2PREP | |
| SCHEMBL2769697 | 0.87 | PREP (0.60) | ALDH1A1NPSR1TP53SMN1; SMN2PREP | |
| SCHEMBL2771120 | 0.84 | MAPT (0.50) | ALDH1A1HTTMMP2PREP | |
| SCHEMBL8805522 | 0.82 | ALDH1A1 (0.45) | ALDH1A1NPSR1TP53GRIN2BPKM | |
| SCHEMBL8805005 | 0.82 | ALDH1A1 (0.45) | ALDH1A1NPSR1TP53GRIN2BPKM | |
| SCHEMBL10390625 | 0.81 | POLB (0.51) | ALDH1A1NPSR1TP53GRIN2BPKM | |
| SCHEMBL7807916 | 0.81 | POLB (0.51) | ALDH1A1NPSR1TP53GRIN2BPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201653-B1 | Method for racemization of optically active azetidine-2-Carboxylate | SUMITOMO CHEMICAL CO (JP) | 2005-04-20 | — | — | EP | disclosed |
| EP-0957089-B1 | Method for racemization of optically active azetidine-2-carboxylate | SUMITOMO CHEMICAL CO (JP) | 2003-09-17 | — | — | EP | disclosed |
| EP-1201653-A1 | Method for racemization of optically active azetidine-2-Carboxylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |
| US-6166224-A | Method for racemization of optically active azetidine-2-carboxylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0957089-A1 | Method for racemization of optically active azetidine-2-carboxylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-11-17 | — | — | EP | disclosed |