Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP7 | P09237 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FABP7 | O15540 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662132 | 0.92 | NPSR1 (0.62) | NPSR1ALDH1A1TP53PREPKDM4E | |
| SCHEMBL6230666 | 0.88 | ALDH1A1 (0.52) | NPSR1ALDH1A1TP53PREPGRIN2B | |
| SCHEMBL20467621 | 0.86 | GFER (0.50) | NPSR1PREPGRIN2BP2RX4SMN1; SMN2 | |
| SCHEMBL10759953 | 0.86 | ALDH1A1 (0.48) | NPSR1ALDH1A1TP53PREPGRIN2B | |
| SCHEMBL10759948 | 0.86 | ALDH1A1 (0.48) | NPSR1ALDH1A1TP53PREPGRIN2B | |
| SCHEMBL3134513 | 0.85 | SMN1; SMN2 (0.61) | NPSR1ALDH1A1PREPSMN1; SMN2NPC1 | |
| SCHEMBL4668774 | 0.85 | SMN1; SMN2 (0.61) | NPSR1ALDH1A1PREPSMN1; SMN2NPC1 | |
| SCHEMBL5702006 | 0.85 | SMN1; SMN2 (0.61) | NPSR1ALDH1A1PREPSMN1; SMN2NPC1 | |
| SCHEMBL20467623 | 0.84 | SMN1; SMN2 (0.47) | NPSR1ALDH1A1PREPSMN1; SMN2NPC1 | |
| SCHEMBL21671228 | 0.84 | SMN1; SMN2 (0.47) | NPSR1ALDH1A1PREPSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313315-B1 | RESOLUTION; ENANTIOMORPHIC PURIFICATION; CRYSTALLIZATION IN SOLVENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1057810-A1 | Method for producing n-protected-azetidine-2-carboxylic acids | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-06 | — | — | EP | disclosed |