Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6425283 | 0.98 | ALDH1A1 (0.48) | ALDH1A1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL11079192 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14609354 | 0.81 | RAB9A (0.39) | ALDH1A1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL23135892 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL14073820 | 0.78 | GLA (0.46) | ALDH1A1RAB9ASMN1; SMN2GAANPC1 | |
| SCHEMBL27767002 | 0.77 | KDM4E (0.47) | ALDH1A1GAAHSD17B10POLBKDM4E | |
| SCHEMBL12790176 | 0.74 | RAB9A (0.64) | ALDH1A1RAB9ASMN1; SMN2GAANPC1 | |
| SCHEMBL11312783 | 0.74 | ALDH1A1 (0.33) | ALDH1A1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL29225341 | 0.74 | ALDH1A1 (0.64) | ALDH1A1HSD17B10 | |
| SCHEMBL6338128 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525003-A1 | METHODS AND CONTRAST AGENTS USEFUL IN QUANTIFYING NITRIC OXIDE | Pharmacia Corporation (US) | 2005-04-27 | — | — | EP | disclosed |
| US-20040092812-A1 | Methods and contrast agents useful in quantifying nitric oxide | JONES CLAUDE R (US) | 2004-05-13 | — | — | US | disclosed |
| WO-2004002536-A1 | METHODS AND CONTRAST AGENTS USEFUL IN QUANTIFYING NITRIC OXIDE | PHARMACIA CORPORATION (US) | 2004-01-08 | — | — | WO | disclosed |
| US-5955586-A | Highly boronated derivatives of texaphyrins | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 1999-09-21 | — | — | US | disclosed |