SCHEMBL6230792

SCHEMBL6230792

c1cc(Oc2ccc(N(CC3CO3)CC3CO3)cc2)ccc1Oc1ccc(N(CC2CO2)CC2CO2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.35
TSHR P16473 3/20 0.35
HIF1A Q16665 2/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HPGD P15428 3/20 0.35
MAPT P10636 2/20 0.35
PKM P14618 2/20 0.35
CYP1A2 P05177 1/20 0.35
PPARG P37231 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
POLB P06746 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6231564 1.00 LMNA (0.41) LMNAMEN1KMT2AMMP1MMP2
SCHEMBL15358774 0.95 ALDH1A1 (0.40) LMNAMEN1KMT2AMMP1MMP2
SCHEMBL6229254 0.95 LMNA (0.39) LMNAMEN1KMT2AMMP1MMP2
SCHEMBL1177607 0.93 TDP1 (0.47) LMNAMEN1KMT2ATDP1ALDH1A1
SCHEMBL14353144 0.93 TDP1 (0.47) LMNAMEN1KMT2ATDP1ALDH1A1
SCHEMBL14353271 0.92 LMNA (0.52) LMNAMEN1KMT2AMMP1MMP2
SCHEMBL554146 0.92 MEN1 (0.49) LMNAMEN1KMT2AMMP1MMP2
SCHEMBL21630227 0.90 TDP1 (0.53) LMNAMEN1KMT2ATDP1ALDH1A1
SCHEMBL19827997 0.90 SMN1; SMN2 (0.47) LMNAMEN1KMT2ATDP1ALDH1A1
SCHEMBL14352937 0.89 LMNA (0.44) LMNAMEN1KMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312812-A1 EPOXY RESIN THE BOEING COMPANY 2023-10-05 US disclosed
US-20230312812-A1 EPOXY RESIN THE BOEING COMPANY 2023-10-05 US disclosed
US-11718707-B2 Epoxy resin THE BOEING COMPANY (US) 2023-08-08 US disclosed
US-11718707-B2 Epoxy resin THE BOEING COMPANY (US) 2023-08-08 US disclosed
WO-2023136269-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-07-20 WO disclosed
US-20210355269-A1 EPOXY RESIN COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2021-11-18 US disclosed
US-11059937-B2 Epoxy resin THE BOEING COMPANY (US) 2021-07-13 US disclosed
US-20190248953-A1 EPOXY RESIN THE BOEING COMPANY 2019-08-15 US disclosed
WO-2018018070-A1 EPOXY RESIN THE BOEING COMPANY (US) 2018-02-01 WO disclosed
EP-0840161-B1 LIQUID CRYSTAL ALIGNING AGENT JSR CORP (JP) 2005-04-06 EP disclosed
US-5969055-A MIXTURES OF POLYAMIC ACIDS AND IMIDIZED POLYMERS FROM THE DEHYDRATION AND RING CLOSURE OF POLYAMIC ACID, THE POLYMERS HAVING HIGHER IMIDIZATION DEGREE ALSO HAVE SMALLER SURFACE FREE ENERGY, FILMS, HIGH PRETILT ANGLE, LOW IMAGE RETENTION JSR CORPORATION (JP) 1999-10-19 US disclosed
EP-0840161-A1 LIQUID CRYSTAL ALIGNING AGENT JSR Corporation (JP) 1998-05-06 EP disclosed
US-5334662-A Toughness; a cationic electrodeposition coating TOMOEGAWA PAPER CO., LTD. (JP) 1994-08-02 US disclosed
US-5334661-A Toughness; a cationic electrodeposition coating TOMOEGAWA PAPER CO., LTD. (JP) 1994-08-02 US disclosed
US-5258456-A Epoxy resin and a phenolic hydroxyl group-containing aramid, polybutadiene-acrylonitrile block copolymer TOMOEGAWA PAPER CO., LTD. (JP) 1993-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718707-B2 Epoxy resin EPHX2, EPHX1, CBR1 LMNA 954/4885MEN1 4762/4885KMT2A 2793/4885
US-20210355269-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 LMNA 954/4885MEN1 4762/4885KMT2A 2793/4885
US-20190248953-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 LMNA 954/4885MEN1 4762/4885KMT2A 2793/4885
US-11059937-B2 Epoxy resin EPHX2, EPHX1, CBR1 LMNA 954/4885MEN1 4762/4885KMT2A 2793/4885
US-20230312812-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 LMNA 954/4885MEN1 4762/4885KMT2A 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.