Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9619284 | 0.74 | HTR2C (0.32) | — | |
| Methane SCHEMBL6064781 | 0.69 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL9172101 | 0.69 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3116458 | 0.67 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL4957540 | 0.67 | GPR3 (0.30) | — | |
| Methane SCHEMBL6065039 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL5083418 | 0.66 | — | — | |
| Methane SCHEMBL6557420 | 0.65 | MEN1 (0.31) | MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL814172 | 0.64 | BCHE (0.36) | — | |
| Hydrochloric Acid SCHEMBL9069597 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511305-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-10-17 | — | — | EP | disclosed |
| EP-1548018-A1 | CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME | Mitsui Chemicals, Inc. (JP) | 2005-06-29 | — | — | EP | disclosed |