Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5589037 | 0.75 | ATM (0.36) | TSHRMAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL6233544 | 0.71 | ALOX5 (0.43) | — | |
| SCHEMBL5588449 | 0.70 | KMT2A (0.37) | TSHRMAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL5587376 | 0.67 | ALDH1A1 (0.35) | TSHRMAPK1CA12CA1CA2 | |
| SCHEMBL29208407 | 0.66 | CYP2A6 (0.37) | MAPK1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL6229354 | 0.66 | ALOX5 (0.44) | — | |
| SCHEMBL3069133 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL5587549 | 0.63 | PTPN1 (0.38) | TSHRMAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL5186784 | 0.62 | ALDH1A1 (0.36) | — | |
| SCHEMBL5587794 | 0.61 | ALDH1A1 (0.35) | TSHRMAPK1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |