SCHEMBL6231039

SCHEMBL6231039

CCOC(CCCOS(=O)(=O)O)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.34
FNTB P49356 2/20 0.34
EPHX1 P07099 1/20 0.33
TP53 P04637 1/20 0.33
CA1 P00915 10/20 0.32
CA2 P00918 10/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MMP9 P14780 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
SMPD1 P17405 3/20 0.32
CA9 Q16790 8/20 0.31
CA12 O43570 3/20 0.31
CA7 P43166 3/20 0.31
CA14 Q9ULX7 3/20 0.31
CA3 P07451 2/20 0.31
CA4 P22748 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049577 0.77 TSHR (0.58) CA1CA2KDM4EUSP2ALDH1A1
SCHEMBL8961105 0.76 RECQL (0.38) FNTAFNTBCA1CA2KDM4E
SCHEMBL4839742 0.75 FNTA (0.38) FNTAFNTBTP53CA1CA2
SCHEMBL13056219 0.74 FNTA (0.35) FNTAFNTBTP53CA1CA2
SCHEMBL22440720 0.74 FNTA (0.37) FNTAFNTBTP53CA1CA2
SCHEMBL6656121 0.73 RECQL (0.59) CA1CA2KDM4EUSP2ALDH1A1
Ammonia Solution, Strong SCHEMBL28278410 0.72 FNTA (0.36) FNTAFNTBTP53CA1CA2
SCHEMBL19734 0.72
SCHEMBL2224608 0.72 TP53 (0.40) FNTAFNTBTP53CA1CA2
SCHEMBL28379507 0.72 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517876-A1 METHOD FOR PRODUCING SUBSTITUTED ORGANIC COMPOUNDS AND USE OF CATALYSTS FOR SUBSTITUTION REACTIONS Solvent Innovation GmbH (DE) 2005-03-30 EP disclosed
WO-2003106379-A1 METHOD FOR PRODUCING SUBSTITUTED ORGANIC COMPOUNDS AND USE OF CATALYSTS FOR SUBSTITUTION REACTIONS SOLVENT INNOVATION GMBH (DE) 2003-12-24 WO disclosed