Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28176122 | 0.98 | PKM (0.37) | PKMALDH1A1 | |
| SCHEMBL4607135 | 0.78 | PKM (0.39) | PKMALDH1A1HSD11B1 | |
| SCHEMBL2547155 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL8947276 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL4533511 | 0.73 | GRIN1 (0.44) | PKM | |
| SCHEMBL27961178 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL9118703 | 0.72 | GRIN1 (0.43) | PKM | |
| SCHEMBL28012598 | 0.72 | ALDH1A1 (0.41) | PKMALDH1A1HSD11B1 | |
| SCHEMBL28507580 | 0.70 | GRIN2D (0.46) | PKM | |
| SCHEMBL8408619 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100339356-C | Aminoadamantane derivatives as therapeutic agents | PANORAMA RES INC (US) | 2007-09-26 | — | — | CN | disclosed |
| EP-1568685-A1 | Aminoadamantane derivatives as therapeutic agents | PANORAMA RESEARCH, INC. (US) | 2005-08-31 | — | — | EP | disclosed |
| EP-1259477-B1 | AMINOADAMANTANE DERIVATIVES AS THERAPEUTIC AGENTS | PANORAMA RES INC (US) | 2005-05-04 | — | — | EP | disclosed |
| CN-1486180-A | Methods for treating neuropsychiatric disorders with NMDA receptor antagonists | 纽热莫勒丘乐有限公司 | 2004-03-31 | — | — | CN | disclosed |
| CN-1446193-A | Aminoadamantane derivatives as therapeutic agents | PANORAMA RES INC (US) | 2003-10-01 | — | — | CN | disclosed |
| CN-1098124-C | Oxidation catalyst system and process for oxidation with the same | DAICEL CHEM (JP) | 2003-01-08 | — | — | CN | disclosed |
| CN-1185757-A | Oxidation catalyst system and oxidation process using the same | DAICEL CHEM (JP) | 1998-06-24 | — | — | CN | disclosed |