Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230832 | 0.81 | PTGER1 (0.44) | BRD4HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4715742 | 0.75 | KDM4E (0.44) | BRD4POLBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3407002 | 0.71 | KDM1A (0.57) | KDM1AMAOAMAOBFEN1ALOX5AP | |
| SCHEMBL1384264 | 0.69 | BRD4 (0.42) | KDM1AMAOAMAOBBRD4HTR1A | |
| SCHEMBL26942219 | 0.69 | KDM1A (0.61) | KDM1AMAOAMAOBHTR1ASLC6A2 | |
| SCHEMBL14882717 | 0.67 | KDM1A (0.60) | KDM1AMAOAMAOBHTR1ASLC6A2 | |
| SCHEMBL8316680 | 0.67 | MAOB (0.55) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL5065124 | 0.66 | KDM1A (0.52) | KDM1AMAOAMAOBFEN1ALOX5AP | |
| SCHEMBL4308528 | 0.66 | KDM1A (0.56) | KDM1AMAOAMAOBFEN1ALOX5AP | |
| SCHEMBL3785631 | 0.65 | L3MBTL1 (0.46) | KDM1AMAOAMAOBFEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076443-A9 | SPIRO COMPOUNDS WITH NPY ANTAGONISTIC ACTIVITY | BANYU PHARMA CO LTD (JP) | 2005-01-20 | — | — | WO | disclosed |
| EP-1483266-A1 | SPIRO COMPOUNDS WITH NPY ANTAGONISTIC ACTIVITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076443-A1 | SPIRO COMPOUNDS WITH NPY ANTAGONISTIC ACTIVITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | WO | disclosed |