Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | PPARA | Q07869 | 5/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231179 | 1.00 | PPARG (0.56) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL13824562 | 0.89 | MAOA (0.71) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL17201749 | 0.89 | MAOA (0.71) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL18291042 | 0.86 | PPARG (0.46) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL18290999 | 0.86 | PPARG (0.46) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL16200011 | 0.85 | ABCB1 (0.53) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL13824956 | 0.84 | MAOA (0.57) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL17201747 | 0.84 | MAOA (0.57) | PPARGPPARAMAOAMAOBCYP19A1 | |
| Chiricanine A SCHEMBL19717932 | 0.83 | MAOA (0.77) | PPARGPPARAMAOAMAOBCYP19A1 | |
| SCHEMBL6234695 | 0.81 | CYP19A1 (0.60) | PPARGPPARAMAOAMAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142216-A1 | Biosynthesis of Phenylpropanoid and Dihydrophenylpropanoid Derivatives | DANSTAR FERMENT AG (CH) | 2018-05-24 | — | — | US | disclosed |
| WO-2016193504-A1 | BIOSYNTHESIS OF PHENYLPROPANOID AND DIHYDROPHENYLPROPANOID DERIVATIVES | EVOLVA SA (CH) | 2016-12-08 | — | — | WO | disclosed |
| EP-1311257-B1 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INC (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1311257-A2 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | Insmed Incorporated (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6552085-B2 | For lowering blood glucose in a mammal | INSMED INCORPORATED | 2003-04-22 | — | — | US | disclosed |
| US-20020058707-A1 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED | 2002-05-16 | — | — | US | disclosed |
| US-20020058701-A1 | Compositions containing hypoglycemically active stilbenoids | SHAMAN PHARMACEUTICALS | 2002-05-16 | — | — | US | disclosed |
| WO-2002013811-A2 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | disclosed |
| WO-2002014252-A2 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058707-A1 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | SLC5A2, SLC5A1, SLC2A1 | PPARG 1187/4885PPARA 479/4885MAOA 1094/4885 |
| US-20020058701-A1 | Compositions containing hypoglycemically active stilbenoids | SLC5A2, SLC5A1, SLC2A1 | PPARG 1187/4885PPARA 479/4885MAOA 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.