Sugi Predict

Sugi Predict / Compounds / SCHEMBL17201747

SCHEMBL17201747

SCHEMBL17201747

CC(C)=CCc1c(O)cc(C=Cc2ccc(O)c(O)c2)c(CC=C(C)C)c1O

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 2/20 0.57
▸ MAOB P27338 2/20 0.57
▸ CYP19A1 P11511 5/20 0.51
▸ PTGS2 P35354 4/20 0.51
▸ ALOX5 P09917 3/20 0.51
▸ PTGS1 P23219 1/20 0.48
▸ PTPN1 P18031 4/20 0.47
▸ LCK P06239 1/20 0.47
▸ MGAM O43451 1/20 0.46
▸ XDH P47989 1/20 0.46
▸ PPARG P37231 5/20 0.46
▸ PPARA Q07869 5/20 0.46
▸ TTR P02766 1/20 0.45
▸ DHODH Q02127 1/20 0.44
▸ OSBP P22059 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13824956 1.00 MAOA (0.57) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL13824562 0.87 MAOA (0.71) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL17201749 0.87 MAOA (0.71) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL13824957 0.86 MAOA (0.61) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL17201740 0.86 MAOA (0.61) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL24074947 0.85 MAOA (0.77) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL6231179 0.84 PPARG (0.56) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL6231177 0.84 PPARG (0.56) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL13825040 0.83 MAOA (0.51) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL25612118 0.81 MAOB (0.55) MAOAMAOBCYP19A1PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11352310-B2 Prenylated hydroxystilbenes Kynan Duke IP, LLC (US) 2022-06-07 — — US disclosed
EP-2709975-B1 PRENYLATED HYDROXYSTILBENES KYNAN DUKE IP LLC (US) 2022-01-12 — — EP disclosed
US-20200331833-A1 PRENYLATED HYDROXYSTILBENES THE UNIVERSITY OF SYDNEY (AU) 2020-10-22 — — US disclosed
US-10696615-B2 Prenylated hydroxystilbenes THE UNIVERSITY OF SYDNEY (AU) 2020-06-30 — — US disclosed
US-20190194105-A1 PRENYLATED HYDROXYSTILBENES THE UNIVERSITY OF SYDNEY (AU) 2019-06-27 — — US disclosed
US-10196335-B2 Prenylated hydroxystilbenes THE UNIVERSITY OF SYDNEY (AU) 2019-02-05 — — US disclosed
US-20150307429-A1 PRENYLATED HYDROXYSTILBENES Kynan Duke IP, LLC 2015-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10196335-B2 Prenylated hydroxystilbenes HMGB2, CYP51A1, CYP8B1 MAOA 4580/4885MAOB 4116/4885CYP19A1 212/4885
US-20200331833-A1 PRENYLATED HYDROXYSTILBENES HSD11B1, HSD3B1, CYP8B1 MAOA 3218/4885MAOB 1156/4885CYP19A1 64/4885
US-20150307429-A1 PRENYLATED HYDROXYSTILBENES HMGB2, CYP51A1, CYP8B1 MAOA 4580/4885MAOB 4116/4885CYP19A1 212/4885
US-10696615-B2 Prenylated hydroxystilbenes HSD11B1, CYP8B1, NR1H2 MAOA 3892/4885MAOB 1089/4885CYP19A1 79/4885
US-11352310-B2 Prenylated hydroxystilbenes HSD11B1, HSD3B1, CYP8B1 MAOA 3218/4885MAOB 1156/4885CYP19A1 64/4885
US-20190194105-A1 PRENYLATED HYDROXYSTILBENES HSD11B1, CYP8B1, NR1H2 MAOA 3892/4885MAOB 1089/4885CYP19A1 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.