Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145549 | 0.85 | DPP4 (0.71) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL6635744 | 0.82 | LMNA (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL29662144 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL136633 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL13414391 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL3252334 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL136634 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL1950144 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL1444728 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E | |
| Gemifloxacin SCHEMBL6930951 | 0.81 | DPP4 (1.00) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068182-B1 | PROCESS FOR PREPARING A PROTECTED 4-AMINOMETHYL-PYRROLIDIN-3-ONE | LG LIFE SCIENCES LTD (KR) | 2005-06-08 | — | — | EP | disclosed |
| US-6307059-B1 | PREPARATION OF QUINOLONE ANTIBIOTICS. | LG CHEMICAL, LTD (KR) | 2001-10-23 | — | — | US | disclosed |
| EP-1068182-A1 | PROCESS FOR PREPARING A PROTECTED 4-AMINOMETHYL-PYRROLIDIN-3-ONE | LG Life Sciences Ltd. (KR) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999044991-A1 | PROCESS FOR PREPARING A PROTECTED 4-AMINOMETHYL-PYRROLIDIN-3-ONE | LG CHEMICAL LTD. (KR) | 1999-09-10 | — | — | WO | disclosed |