Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777598 | 1.00 | RAD52 (0.48) | RAD52TAAR1IDO1HRH1MAOA | |
| SCHEMBL28703223 | 1.00 | RAD52 (0.48) | RAD52TAAR1IDO1HRH1MAOA | |
| SCHEMBL7574477 | 0.98 | RAD52 (0.49) | RAD52TAAR1IDO1HRH1MAOA | |
| SCHEMBL1587764 | 0.92 | IDO1 (0.50) | RAD52TAAR1IDO1DAOTACR1 | |
| SCHEMBL15784839 | 0.89 | RAD52 (0.44) | RAD52TAAR1IDO1MAOADAO | |
| SCHEMBL15787370 | 0.85 | NOS1 (0.48) | RAD52TAAR1IDO1HRH1MAOA | |
| SCHEMBL21514085 | 0.85 | RAD52 (0.41) | RAD52TAAR1IDO1MAOADAO | |
| SCHEMBL626371 | 0.83 | TAAR1 (0.64) | RAD52TAAR1IDO1DAOMAOB | |
| SCHEMBL2095840 | 0.82 | TAAR1 (0.74) | TAAR1IDO1MAOADAOMAOB | |
| SCHEMBL6235879 | 0.82 | TAAR1 (0.74) | TAAR1IDO1MAOADAOMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |
| EP-0709376-B1 | Phenylpiperidino derivatives as neurokinin antagonists | ASTRAZENECA AB (SE) | 2003-07-23 | — | — | EP | disclosed |
| EP-0709376-A2 | Therapeutic compounds | ZENECA LIMITED (GB) | 1996-05-01 | — | — | EP | disclosed |