Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 2/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649344 | 0.98 | ABL1 (0.51) | ABL1TLR8KCNH3MAPTCYP1A2 | |
| SCHEMBL19968723 | 0.98 | ABL1 (0.51) | ABL1TLR8KCNH3MAPTCYP1A2 | |
| SCHEMBL27642277 | 0.94 | F2R (0.48) | ABL1TLR8MAPTCYP1A2CYP3A4 | |
| Boric Acid SCHEMBL27802341 | 0.92 | ABL1 (0.47) | ABL1TLR8KCNH3HTTHPGD | |
| Boric Acid SCHEMBL27802342 | 0.92 | ABL1 (0.47) | ABL1TLR8KCNH3HTTHPGD | |
| SCHEMBL3662823 | 0.88 | ABL1 (0.54) | ABL1KCNH3MAPTCYP1A2CYP3A4 | |
| SCHEMBL6235610 | 0.86 | MAPT (0.50) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL5857094 | 0.85 | MAPT (0.48) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8667014 | 0.82 | F2R (0.56) | ABL1TLR8KCNH3MAPTCYP1A2 | |
| SCHEMBL20197373 | 0.81 | MAPT (0.71) | ABL1KCNH3MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |