Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 2/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609022 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15231967 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29565935 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15229858 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15230385 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5597408 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9116266 | 0.98 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3440754 | 0.94 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31519377 | 0.94 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3662823 | 0.88 | ABL1 (0.54) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056799-A | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, using and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2017-08-18 | — | — | CN | claimed |
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |
| CN-107056799-A | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, using and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2017-08-18 | — | — | CN | disclosed |