Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263674 | 1.00 | TAAR1 (0.71) | TAAR1MAOADRD2SLC6A4SLC6A3 | |
| SCHEMBL29263635 | 1.00 | TAAR1 (0.71) | TAAR1MAOADRD2SLC6A4SLC6A3 | |
| SCHEMBL1317595 | 0.92 | TAAR1 (0.77) | TAAR1MAOADRD2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5857097 | 0.90 | TAAR1 (0.74) | TAAR1MAOADRD2SLC6A4SLC6A3 | |
| SCHEMBL7857344 | 0.86 | TAAR1 (0.62) | TAAR1DRD2SLC6A4SLC6A3IDO1 | |
| SCHEMBL30957025 | 0.86 | MAOA (0.67) | TAAR1MAOADRD2HRH1 | |
| SCHEMBL29429505 | 0.84 | TAAR1 (1.00) | TAAR1DRD2SLC6A3MAOBIDO1 | |
| SCHEMBL146545 | 0.84 | TAAR1 (1.00) | TAAR1DRD2SLC6A3MAOBIDO1 | |
| SCHEMBL16038467 | 0.82 | TAAR1 (0.67) | TAAR1DRD2SLC6A4SLC6A3MAOB | |
| Hydrochloric Acid SCHEMBL5728333 | 0.82 | TAAR1 (0.96) | TAAR1DRD2SLC6A3MAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |