SCHEMBL6231622

SCHEMBL6231622

CCCC1=CC=CC(=O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6686506 0.88 ACHE (0.43) ACHEBACE1
SCHEMBL27436500 0.86
SCHEMBL19461836 0.84 ACHE (0.53) ACHEBACE1
SCHEMBL13015757 0.84 ACHE (0.53) ACHEBACE1
SCHEMBL11076693 0.84 ACHE (0.53) ACHEBACE1
SCHEMBL11775122 0.82
SCHEMBL10402896 0.78
SCHEMBL29777288 0.78
SCHEMBL5588713 0.76 CA2 (0.33) ACHEBACE1
SCHEMBL27717977 0.74 ACHE (0.50) ACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018315-B2 Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-06-25 US disclosed
US-20200377929-A1 PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2020-12-03 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed
US-3970640-A Process for the production of polyphenylene ethers having a desired polymerization degree MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-07-20 US disclosed