Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.51 |
| ▸ | PDE4A | P27815 | 11/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228583 | 0.86 | PDE4A (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL497761 | 0.83 | SMN1; SMN2 (0.52) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL4728355 | 0.82 | PDE4B (0.56) | FFAR1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6231781 | 0.81 | PDE4B (0.48) | FFAR1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6232542 | 0.79 | PDE4A (0.53) | FFAR1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6231350 | 0.78 | PDE4B (0.48) | FFAR1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6229294 | 0.77 | PDE4A (0.51) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL6229093 | 0.76 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL6227557 | 0.76 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL6228902 | 0.76 | PDE4A (0.49) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933366-B1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-6235739-B1 | ANTIINFLAMMATORY AGENTS; ANTIHISTAMINES; SKIN DISORDERS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0933366-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-08-04 | — | — | EP | disclosed |