Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL346159 | 0.98 | ALDH1A1 (0.55) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL149569 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL10955534 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL8102518 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL356416 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL317072 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL317433 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL10814643 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL7293653 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E | |
| SCHEMBL3252003 | 0.96 | FASN (0.59) | FASNALDH1A1TSHRFAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050271735-A1 | Method of encapsulating hydrophobic organic molecules in polyurea capsules | MCMASTER UNIVERSITY (CA) | 2005-12-08 | — | — | US | claimed |
| EP-1517746-A1 | METHOD OF ENCAPSULATING HYDROPHOBIC ORGANIC MOLECULES IN POLYUREA CAPSULES | McMaster University (CA) | 2005-03-30 | — | — | EP | claimed |
| WO-2003101606-A1 | METHOD OF ENCAPSULATING HYDROPHOBIC ORGANIC MOLECULES IN POLYUREA CAPSULES | MCMASTER UNIVERSITY (CA) | 2003-12-11 | — | — | WO | claimed |
| US-20050271735-A1 | Method of encapsulating hydrophobic organic molecules in polyurea capsules | MCMASTER UNIVERSITY (CA) | 2005-12-08 | — | — | US | disclosed |
| EP-1517746-A1 | METHOD OF ENCAPSULATING HYDROPHOBIC ORGANIC MOLECULES IN POLYUREA CAPSULES | McMaster University (CA) | 2005-03-30 | — | — | EP | disclosed |
| WO-2003101606-A1 | METHOD OF ENCAPSULATING HYDROPHOBIC ORGANIC MOLECULES IN POLYUREA CAPSULES | MCMASTER UNIVERSITY (CA) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271735-A1 | Method of encapsulating hydrophobic organic molecules in polyurea capsules | PUF60, HNRNPU, HNRNPUL1 | FASN 463/4885ALDH1A1 1938/4885TSHR 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.