Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | FASN | P49327 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6231697 | 0.98 | FASN (0.55) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL10445275 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL9786201 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL1404382 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL3687811 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL16986053 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL2111943 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL1806493 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL10445274 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E | |
| SCHEMBL345369 | 0.96 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084734-B2 | Peptide personal care compositions and methods for their use | DANISCO US INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-20150152404-A1 | PROTEASES PRODUCING AN ALTERED IMMUNOLOGICAL RESPONSE AND METHODS OF MAKING AND USING THE SAME | DANISCO US INC (US) | 2015-06-04 | — | — | US | disclosed |
| US-8962796-B2 | Modified variant Bowman Birk protease inhibitors | DANISCO US INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140294881-A1 | PROTEASES PRODUCING AN ALTERED IMMUNOLOGICAL RESPONSE AND METHODS OF MAKING AND USING THE SAME | DANISCO US INC. (US) | 2014-10-02 | — | — | US | disclosed |
| US-20140186922-A1 | PROTEASES PRODUCING AN ALTERED IMMUNOGENIC RESPONSE AND METHODS OF MAKING AND USING THE SAME | DANISCO US INC. (US) | 2014-07-03 | — | — | US | disclosed |
| US-20130216519-A1 | PROTEASES PRODUCING AN ALTERED IMMUNOGENIC RESPONSE AND METHODS OF MAKING AND USING THE SAME | DANISCO US INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130195781-A1 | Modified Variant Bowman Birk Protease Inhibitors | DANISCO US INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130065829-A1 | PEPTIDES AND SUPPORTED PEPTIDES FOR TREATING SKIN DISEASES | DANISCO US INC. (US) | 2013-03-14 | — | — | US | disclosed |
| US-8394941-B2 | Modified variant Bowman Birk Protease Inhibitors | DANISCO US INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120014885-A1 | Personal Care Compositions and Methods for Their Use | DANISCO US INC. | 2012-01-19 | — | — | US | disclosed |
| EP-1317250-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1317248-A1 | COSMETIC METHOD | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1317249-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1317246-A1 | COSMETIC METHOD | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002077187-A2 | PROTEINS PRODUCING AN ALTERED IMMUNOGENIC RESPONSE AND METHODS OF MAKING AND USING THE SAME | GENENCOR INTERNATIONAL, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| WO-2002022102-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002022100-A1 | COSMETIC METHOD | THE PROCTER & GAMBLE COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002022103-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002022101-A1 | COSMETIC METHOD | THE PROCTER & GAMBLE COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002022099-A1 | COSMETIC METHOD FOR TREATMENT OF SKIN AND/OR HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014885-A1 | Personal Care Compositions and Methods for Their Use | CUTA, VEGFA, BDNF | ALDH1A1 2167/4885TSHR 2993/4885FASN 4389/4885 |
| US-20130195781-A1 | Modified Variant Bowman Birk Protease Inhibitors | SERPINB1, BBC3, BRAP | ALDH1A1 4735/4885TSHR 4485/4885FASN 4565/4885 |
| US-20130065829-A1 | PEPTIDES AND SUPPORTED PEPTIDES FOR TREATING SKIN DISEASES | VEGFA, FLT1, KDR | ALDH1A1 3347/4885TSHR 2984/4885FASN 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.