Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229695 | 0.77 | PDE4B (0.37) | MAPTALDH1A1CYP3A4TDP1GAA | |
| SCHEMBL6228357 | 0.74 | SMN1; SMN2 (0.42) | MAPTALDH1A1CYP3A4TDP1GAA | |
| SCHEMBL20049214 | 0.73 | MAPT (0.53) | MAPTTSHRALOX15ATMALDH1A1 | |
| SCHEMBL3123406 | 0.73 | ALDH1A1 (0.67) | MAPTTSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL31210403 | 0.70 | MAPT (0.50) | MAPTTSHRALOX15ATMALDH1A1 | |
| SCHEMBL1986974 | 0.70 | GAA (0.35) | MAPTALDH1A1GAARAB9ANPC1 | |
| SCHEMBL21098160 | 0.70 | MAPT (0.50) | MAPTTSHRALOX15ATMALDH1A1 | |
| SCHEMBL19699121 | 0.69 | MAPT (0.49) | MAPTTSHRALOX15ATMALDH1A1 | |
| SCHEMBL5069181 | 0.69 | — | — | |
| SCHEMBL20049465 | 0.68 | MAPT (0.48) | MAPTTSHRALOX15ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |