Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8981831 | 0.94 | LMNA (0.52) | PPARAPTPN1PPARGALDH1A1NPSR1 | |
| SCHEMBL8981845 | 0.94 | LMNA (0.52) | PPARAPTPN1PPARGALDH1A1NPSR1 | |
| SCHEMBL8981839 | 0.94 | LMNA (0.52) | PPARAPTPN1PPARGALDH1A1NPSR1 | |
| SCHEMBL13524845 | 0.92 | PTPN1 (0.55) | PPARAPTPN1PPARGALDH1A1NPSR1 | |
| SCHEMBL13847876 | 0.91 | PTPN1 (0.54) | PPARAPTPN1PPARGALDH1A1NPSR1 | |
| SCHEMBL6232300 | 0.90 | PTPN1 (0.49) | PPARAPTPN1PPARGALDH1A1NPSR1 | |
| SCHEMBL6376424 | 0.89 | POLB (0.54) | PPARAPTPN1PPARGALDH1A1LMNA | |
| SCHEMBL6374920 | 0.88 | PPARA (0.57) | PPARAPTPN1PPARGALDH1A1LMNA | |
| SCHEMBL3922 | 0.87 | PPARA (0.61) | PPARAPTPN1PPARG | |
| SCHEMBL6233615 | 0.87 | PTPN1 (0.51) | PPARAPTPN1PPARGCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207158-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | claimed |
| US-6780431-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONISTS; METABOLIC DISEASES SUCH AS DIABETES AND HYPERLIPIDEMIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-08-24 | — | — | US | claimed |
| EP-1207158-A1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | claimed |